FISH OIL INHIBITS CORONARY ARTERY DISEASE.

In a study conducted by Skejby University Hospital et al., researchers administered a 1-percent fish oil diet (high in omega-3 polyunsaturated fatty acids) or a 1-percent corn oil diet (high in omega-6 fatty acids) to 63 LDL receptor-deficient (LDLR) mice and 69 mice deficient in apolipoprotein. While both groups had lower levels of LDL cholesterol and triglycerides, coronary artery disease was significantly reduced in the fish oil group compared with the corn oil group when evaluated en face (a staining method) in the aortic arch. The authors concluded omega-3 and omega-6 supplementation retarded the development of coronary artery disease in LDLR mice, with a stronger effect seen with omega-3 PUFA. (Natural Products Insider, Jan. 2006)